Bonnie F Sloane Selected Research

Enzymes

10/2013	Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.
1/2012	RNA-Seq of human breast ductal carcinoma in situ models reveals aldehyde dehydrogenase isoform 5A1 as a novel potential target.
9/2009	Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis.
11/2008	Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts.
11/2004	Cysteine cathepsins in human cancer.
6/2003	Pericellular cathepsin B and malignant progression.
1/2003	Cathepsin B and its role(s) in cancer progression.

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Bonnie F Sloane Research Topics

Disease

57	Neoplasms (Cancer) 03/2021 - 03/2002
26	Breast Neoplasms (Breast Cancer) 11/2021 - 08/2002
17	Neoplasm Metastasis (Metastasis) 01/2019 - 01/2003
9	Carcinoma (Carcinomatosis) 08/2015 - 03/2002
8	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2018 - 12/2009
5	Carcinogenesis 12/2017 - 01/2012
5	Prostatic Neoplasms (Prostate Cancer) 03/2009 - 08/2004
4	Inflammatory Breast Neoplasms 11/2015 - 01/2011
3	Glioma (Gliomas) 06/2014 - 09/2002
3	Glioblastoma (Glioblastoma Multiforme) 08/2004 - 09/2002
2	Acidosis 10/2013 - 03/2013
2	Breast Ductal Carcinoma 01/2012 - 12/2009
2	Colonic Neoplasms (Colon Cancer) 02/2008 - 04/2005
2	Colorectal Neoplasms (Colorectal Cancer) 04/2005 - 11/2003
1	Lymphatic Metastasis 11/2021
1	Esophageal Neoplasms (Esophageal Cancer) 11/2015
1	Cystic Fibrosis (Mucoviscidosis) 12/2014
1	Rheumatoid Arthritis 03/2014
1	Infections 03/2014
1	Triple Negative Breast Neoplasms 01/2014
1	Joint Diseases (Joint Disease) 02/2013
1	Hyperplasia 12/2012
1	Neurofibrosarcoma (MPNST) 04/2011
1	Inflammation (Inflammations) 09/2009
1	Circulating Neoplastic Cells 03/2009
1	Experimental Melanoma 03/2009

Drug/Important Bio-Agent (IBA)

26	Peptide Hydrolases (Proteases)FDA Link 01/2019 - 03/2002
24	Cathepsin BIBA 12/2017 - 07/2002
14	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2003
11	Cysteine Proteases (Cysteine Protease)IBA 01/2015 - 07/2002
10	CathepsinsIBA 12/2017 - 08/2002
10	CollagenIBA 01/2015 - 08/2002
9	Cysteine (L-Cysteine)FDA Link 12/2017 - 11/2004
7	EnzymesIBA 10/2013 - 01/2003
5	CytokinesIBA 03/2021 - 09/2009
4	Protease Inhibitors (Protease Inhibitor)IBA 12/2017 - 01/2006
4	Biomarkers (Surrogate Marker)IBA 01/2017 - 02/2008
3	Conditioned Culture MediaIBA 03/2021 - 12/2009
3	ChemokinesIBA 03/2021 - 01/2014
3	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2017 - 11/2003
3	Interleukin-6 (Interleukin 6)IBA 01/2017 - 01/2010
3	Plasminogen Activators (Plasminogen Activator)IBA 01/2017 - 11/2003
3	AcidsIBA 10/2013 - 03/2009
3	Messenger RNA (mRNA)IBA 01/2012 - 01/2003
3	Cathepsin KIBA 09/2009 - 08/2006
3	Matrix Metalloproteinases (MMPs)IBA 08/2006 - 04/2005
3	Annexin A2 (Annexin II)IBA 11/2003 - 09/2002
3	procathepsin BIBA 06/2003 - 08/2002
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 04/2004
2	N- (3- propylcarbamoyloxirane- 2- carbonyl)- isoleucyl- prolineIBA 12/2017 - 03/2012
2	Cystatin AIBA 12/2017 - 03/2012
2	Urokinase Plasminogen Activator ReceptorsIBA 01/2017 - 11/2003
2	Talaporfin (talaporfin sodium)IBA 11/2015 - 04/2004
2	Glutamic Acid (Glutamate)FDA Link 01/2014 - 01/2012
2	Bicarbonates (Hydrogen Carbonate)IBA 10/2013 - 03/2009
2	Glucose (Dextrose)FDA LinkGeneric 03/2013 - 03/2009
2	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 03/2013 - 08/2012
2	RNA (Ribonucleic Acid)IBA 01/2012 - 05/2007
2	Protein Isoforms (Isoforms)IBA 01/2012 - 08/2004
2	Caveolin 1IBA 01/2011 - 04/2005
2	Cell Surface ReceptorsIBA 09/2008 - 04/2005
2	Collagen Type IV (Type IV Collagen)IBA 09/2008 - 07/2003
2	Cystatin MIBA 10/2004 - 03/2004
1	Phosphotransferases (Kinase)IBA 01/2018
1	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 01/2018
1	Mitogen-Activated Protein KinasesIBA 01/2018
1	Plasminogen Activator Inhibitor 1IBA 01/2017
1	cabozantinibIBA 02/2016
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2015
1	AntibodiesIBA 03/2015
1	RutheniumIBA 01/2015
1	Coloring Agents (Dyes)IBA 01/2015
1	NitrilesIBA 01/2015
1	ErbB Receptors (EGF Receptor)IBA 01/2014
1	metabotropic glutamate receptor type 1IBA 01/2014
1	Monoclonal AntibodiesIBA 01/2014
1	Hormones (Hormone)IBA 01/2014
1	Estrogen ReceptorsIBA 01/2014
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2014
1	Cathepsin CIBA 10/2013
1	Serine (L-Serine)FDA Link 10/2013
1	HydrogenIBA 03/2013
1	SodiumIBA 03/2013
1	cathepsin SIBA 02/2013
1	JPM 565IBA 03/2012
1	CyclinsIBA 01/2012
1	Aldehyde DehydrogenaseIBA 01/2012
1	TransferasesIBA 04/2011
1	Lovastatin (Mevacor)FDA LinkGeneric 04/2011
1	Biological FactorsIBA 10/2010
1	oxidized low density lipoproteinIBA 01/2010
1	CholesterolIBA 01/2010
1	2,5-dichloro-4-bromophenol (B 2)IBA 01/2010
1	Neutralizing AntibodiesIBA 01/2010
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2009

Therapy/Procedure

10	Therapeutics 11/2021 - 03/2004
2	Injections 03/2021 - 03/2009
1	Precision Medicine 01/2019
1	Photochemotherapy (Photodynamic Therapy) 11/2015
1	Oral Administration 03/2013